#150: MEWTWO

scientificpokedex:

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Mewtwo is a Pokémon that was created by genetic manipulation. However, even though the scientific power of humans created this Pokémon’s body, they failed to endow Mewtwo with a compassionate heart.

Mewtwo is the product of decades of genetic engineering. Years of gene decoding, splicing, and cloning gave birth to the strongest and quite possibly the most tragic pokemon to date. What’s more, there are heavy implications that Mewtwo was not just cloned from Mew, but is part human as well.

DNA is the basic component for all genomes. Within the double stranded helix, every bit of information you can think of is present. What texture of hair, what colors you can see, if you have scales, resistance to certain diseases, and anything else you can’t think of that makes you, you is inside the DNA.

Cloning is relatively easy: genetic engineering, on the other hand, is not. The whole intent behind Mewtwo was to create the strongest pokemon possible. This is IV breeding to the extreme. To do this, scientists would have to decode the entire genome sequence of Mew, to determine what traits they wanted to keep, and what not. Keep the strength. Toss the cute. Funnel and focus the psychic ability. Dump the natural innocence.

Once you’ve managed to sequence the DNA and isolate the pieces you want, the next step is extracting it. This is most commonly done through a process called PCR, Polymerase Chain Reaction. This is an extremely specific process that usually involves 20-30 repeated temperature cycles. Because of this, PCR machines have been invented to automate the temperature of the sample in these cycles.

Essentially, the sample is heated quickly such that the DNA strand splits apart. This allows a specially engineered primer to enter in, and locate the target sequence. Think of the primer like a puzzle piece. It only fits one place in the DNA, where it will gladly connect. The primer, however, is just the starting point. Once it attaches, free nucleotides will come in and attach themselves to the primer, creating an extended exact copy of the desired gene sequence, at which point it will leave and the DNA strand will zip itself back together.

After that, the newly-created copies of the target gene sequences can be inserted into another organism. Or more commonly, embyros. The engineered embryo was implanted into Mew, and on February 6th, Mewtwo was born.

This method has been used to create glow in the dark rabbits, Jurassic Park style chicken egg dinosaurs, or the harsh and powerful Mewtwo.

All it takes is DNA.

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